The HE4 OVARIAN CANCER Test: A Comprehensive Guide for Early Detection and Management

**Name Synonyms:** HE4, Human Epididymis Protein 4, Epididymis Protein 4 **Conditions and Disease:** Ovarian cancer **Symptoms:** Bloating, pelvic or abdominal pain, difficulty eating or feeling full quickly, unexplained weight loss, fatigue, back pain, changes in bowel habits, frequent urination **What the Test Can Identify:** Elevated levels of HE4 protein in the blood **Organ Tested:** Ovaries **Keywords:** HE4, Ovarian cancer, Tumor marker, Early detection, Biomarker, Diagnosis

## The HE4 OVARIAN CANCER Test: A Comprehensive Guide for Patients

### Introduction

The HE4 OVARIAN CANCER test is a valuable tool in diagnosing and managing ovarian cancer. It detects elevated protein levels in the blood, helping healthcare providers identify the condition early, increasing treatment success chances.

**Name Synonyms:** HE4, Human Epididymis Protein 4, Epididymis Protein 4

### Test Overview

The HE4 OVARIAN CANCER test measures the human epididymis protein 4 (HE4) concentration in the blood. HE4 is produced by the epididymis but can also be elevated in women with ovarian cancer.

**Organ Tested:** Ovaries

### Detected Conditions and Diseases

The HE4 OVARIAN CANCER test is used primarily to detect ovarian cancer. It can be used:

* To screen high-risk women: Women with a family history of ovarian cancer or associated genetic mutations can benefit from regular HE4 screening.
* To diagnose ovarian cancer: The test confirms a diagnosis when other symptoms or findings suggest the disease’s presence.
* To monitor treatment: HE4 levels can be tracked during and after treatment to assess therapy effectiveness.

### Preparation Guidelines

Before the HE4 OVARIAN CANCER test, patients should:

* Fast for at least 8 hours.
* Inform their healthcare provider about any medications or supplements they are taking.
* Avoid strenuous activity for 24 hours before the test.

### Procedure

The HE4 OVARIAN CANCER test is a simple blood draw. A small amount of blood is collected from a vein in the arm. The procedure is quick and painless.

### Duration and Waiting Time

The blood draw takes a few minutes. The blood sample is analyzed in a laboratory. Results are typically available within 1-2 weeks.

### Additional Tests

The HE4 OVARIAN CANCER test may be combined with other tests, such as:

* **CA-125:** Another tumor marker used to screen for and diagnose ovarian cancer.
* **Transvaginal ultrasound:** An imaging test that visualizes the ovaries and uterus.
* **Biopsy:** A procedure that removes a small tissue sample from the ovaries for microscopic examination.

### Conclusion

The HE4 OVARIAN CANCER test is a valuable screening and diagnostic tool for ovarian cancer. By detecting elevated HE4 levels, it helps healthcare providers identify the condition early, when treatment is most effective. Patients with a family history of ovarian cancer or other risk factors should consider discussing the HE4 test with their healthcare provider.

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