CORT FREE Test: A Comprehensive Guide for Patients
Introduction
The CORT FREE test is a lab test that measures the level of free cortisol in the body. Cortisol is a hormone produced by the adrenal glands, located on top of the kidneys. It plays a crucial role in regulating several bodily functions, including:
- Metabolism
- Blood pressure
- Immune response
- Stress response
The CORT FREE test is often used to diagnose Cushing’s syndrome and Addison’s disease, both of which affect cortisol production.
Test Overview
The CORT FREE test measures the level of cortisol not bound to proteins in the blood. Only free cortisol can exert its effects on the body.
The test is usually performed in the morning, when cortisol levels are highest. A small blood sample is drawn from a vein in the arm.
Conditions and Diseases Detected
The CORT FREE test can help diagnose the following conditions:
- Cushing’s syndrome: Overproduction of cortisol. Symptoms include weight gain, fatigue, muscle weakness, high blood pressure, and diabetes.
- Addison’s disease: Underproduction of cortisol. Symptoms include fatigue, weight loss, nausea, vomiting, and low blood pressure.
- Pituitary disorders: Problems with the pituitary gland, located at the brain’s base, can affect cortisol production. Symptoms may include changes in weight, mood, and menstrual cycles.
Preparation Guidelines
No special preparation is required for the CORT FREE test. However, inform your doctor about any medications you’re taking that could affect cortisol levels.
Procedure
The CORT FREE test is a simple and safe procedure. A small blood sample is drawn from a vein in the arm and sent to a lab for analysis.
Duration and Waiting Time
The test takes about 10 minutes to complete. Results are typically available within a few days.
Additional Tests
Your doctor may order additional tests along with the CORT FREE test to aid in diagnosis, such as:
- ACTH stimulation test: Measures ACTH (adrenocorticotropic hormone) levels in the blood, which stimulates cortisol production.
- Dexamethasone suppression test: Measures cortisol levels in the blood after taking dexamethasone, a medication that suppresses cortisol production.
Conclusion
The CORT FREE test is a valuable tool for diagnosing Cushing’s syndrome, Addison’s disease, and other conditions that affect cortisol production. Consult your doctor if you experience symptoms of these conditions to determine if the CORT FREE test is appropriate for you.
