Prematurity and Low Birth Weight: A Comprehensive Guide for Medical Professionals

## Prematurity and Low Birth Weight: A Comprehensive Guide

### Introduction

Prematurity, or preterm birth, refers to the delivery of a baby before 37 completed weeks of gestation. Low birth weight (LBW) is a condition in which a newborn weighs less than 2,500 grams (5 pounds, 8 ounces) at birth. Extreme prematurity and LBW can lead to serious health complications for the baby.

### Symptoms

**Preterm birth:**
– Respiratory distress
– Apnea (pauses in breathing)
– Bradycardia (slow heart rate)
– Hypothermia (low body temperature)

**LBW:**
– Hyperbilirubinemia (jaundice)
– Hypoglycemia (low blood sugar)
– Necrotizing enterocolitis (NEC) (inflammation and damage to the intestine)
– Intraventricular hemorrhage (IVH) (bleeding in the brain)

### Diagnosis

Prematurity and LBW are diagnosed based on the baby’s gestational age and birth weight. Gestational age is determined by the mother’s last menstrual period, ultrasound measurements, or a physical examination of the baby. Birth weight is measured immediately after delivery.

**Tests:**

– Ultrasound: Can determine gestational age and check for signs of fetal growth restriction (FGR) or intrauterine growth restriction (IUGR).
– Amniocentesis: May be used to check for genetic abnormalities or infections.

### Prevention

**Maternal risk factors:**
– Young maternal age (<18 years) - Advanced maternal age (>35 years)
– Multiple pregnancies
– Pregnancy complications (e.g., preeclampsia, gestational diabetes)

**Fetal risk factors:**
– Genetic abnormalities
– Intrauterine infections
– Placental problems

### Treatment

Premature and LBW infants typically require specialized care in a neonatal intensive care unit (NICU). Treatment may include:

– Mechanical ventilation
– Oxygen therapy
– Phototherapy (light therapy)
– Intravenous (IV) fluids
– Enteral feeding

### Vaccinations

Preterm infants may require additional vaccines to protect against infections, such as:
– Rotavirus vaccine
– Influenza vaccine
– Meningococcal B vaccine

### Complications

**Short-term:**
– Respiratory problems (e.g., chronic lung disease)
– Jaundice
– Retinopathy of prematurity (ROP) (eye damage)

**Long-term:**
– Developmental disabilities
– Neurocognitive impairment
– Cerebral palsy

### Doctors Typically Involved

* Obstetrician/Gynecologist (OB/GYN)
* Neonatologist
* Pediatrician

### Related Terms

– Preterm labor: Labor that begins before 37 weeks of gestation.
– Preterm delivery: The birth of a baby before 37 weeks of gestation.
– Fetal growth restriction (FGR): A condition in which the fetus does not grow at a normal rate.
– Intrauterine growth restriction (IUGR): Another term for FGR.