Cleft Lip: Causes, Diagnosis, Types, Treatment, and Prognosis

## Cleft Lip: A Comprehensive Guide

### Introduction

Cleft lip is a birth defect that occurs when the tissues of the upper lip do not fully fuse during pregnancy. This can result in a variety of openings or gaps in the lip, which may extend into the nose or hard palate (roof of the mouth).

**Symptoms:**

– Opening or gap in the upper lip
– Difficulty feeding due to a gap in the palate
– Speech problems caused by air leakage during speaking

### Diagnosis and Prevention

Diagnosing cleft lip typically involves a physical examination by a pediatrician or plastic surgeon. Additional tests may include:

– **Ultrasound:** To detect cleft lip in utero
– **Amniocentesis or Chorionic Villus Sampling (CVS):** Genetic tests to identify potential genetic causes

Prevention of cleft lip is limited but may include:

– Taking folic acid supplements during pregnancy
– Avoiding alcohol and smoking during pregnancy
– Managing underlying medical conditions, such as diabetes and hypertension

### Types of Cleft Lip

**Cleft lip with or without cleft palate**

– Cleft lip and cleft palate (separation of the palate)
– Isolated cleft lip (cleft lip without cleft palate)

**Unilateral cleft lip**

– Gap in one side of the lip
– **Complete cleft lip:** Gap extends into the nose
– **Incomplete cleft lip:** Gap does not extend into the nose
– **Microform cleft lip:** Small notch or gap in the lip

**Bilateral cleft lip**

– Gap in both sides of the lip
– Can be **complete** or **incomplete**

### Treatment

Treatment for cleft lip typically involves surgery.

**Cheiloplasty (Cleft Lip Repair):**

– Performed between 2-6 months of age
– Goal is to close the gap in the lip and restore the normal shape and function
– Performed by a plastic surgeon specializing in craniofacial surgery

**Palatoplasty (Cleft Palate Repair):**

– Performed between 6-12 months of age
– Goal is to close the gap in the palate and restore normal speech and feeding
– Performed by a plastic surgeon specializing in craniofacial surgery

**Additional Treatment:**

– **Antibiotics:** To prevent infection
– **Speech Therapy:** To improve speech and communication
– **Orthodontics:** To correct dental problems
– **Orthognathic Surgery:** To correct jaw and facial deformities
– **Alveolar Bone Grafting:** To provide support for missing teeth
– **Rhinoplasty:** To repair nasal deformities
– **Gene Therapy:** Under research and development

### Complications

Complications of cleft lip surgery may include:

– Infection
– Scarring
– Lip asymmetry
– Nasal deformity
– Speech difficulties
– Dental problems

### Prognosis

The prognosis for cleft lip is generally good with early diagnosis and treatment. Most individuals with cleft lip can live full and healthy lives with minimal complications.